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1

Application of Stable Isotope Tracer Combined with Mass Spectrometric Detection for Studyingmyo-Inositol Uptake by Cultured Neurons from Fetal Mouse: Effect of Trisomy 16

Acevedo, Larisa D., Holloway, Harold W., Rapoport, Stanley I., Umesha Shetty, H.

Journal:

Journal of Mass Spectrometry

Year:

1997

Language:

english

File:

PDF, 353 KB

english, 1997

2

Use of LC–MS–MS for the rapid, specific and sensitive quality control measurement of carrier in a PET radioligand: [18F]FECNT

H. Umesha Shetty, Frederick T. Chin, John L. Musachio, Victor W. Pike

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

3

Development of chemically interesterified healthy coconut oil blends

Nasirullah, Rizwan Shariff, Umesha Shankara Shetty, Reddy Sunki Yella

Journal:

International Journal of Food Science & Technology

Year:

2010

Language:

english

File:

PDF, 626 KB

english, 2010

4

Chronic exposure of neural cells to elevated intracellular sodium decreases mitochondrial mRNA expression

Krish Chandrasekaran, Li-Ing Liu, Kimmo Hatanpää, Umesha Shetty, Zara Mehrabian, Peter D Murray, Gary Fiskum, Stanley I Rapoport

Journal:

Year:

2001

Language:

english

File:

PDF, 722 KB

english, 2001

5

Piperazine ring cleavage in the electron impact induced fragmentation of piperazine type phenothiazine antipsychotic agents

H. Umesha Shetty, Edward M. Hawes, Kamal K. Midha

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1983

Language:

english

File:

PDF, 503 KB

english, 1983

6

Assay of myo-inositol in cerebrospinal fluid and plasma by chemical ionization mass spectrometry of the hexaacetate derivative

H. Umesha Shetty, Harold W. Holloway

Journal:

Biological Mass Spectrometry = Journal of Mass Spectrometry (Wiley)

Year:

1994

Language:

english

File:

PDF, 463 KB

english, 1994

7

Automated radiosynthesis of [18F]SPA-RQ for imaging human brain NK1 receptors with PET

Frederick T. Chin, Cheryl L. Morse, H. Umesha Shetty, Victor W. Pike

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2006

Language:

english

File:

PDF, 316 KB

english, 2006

8

Stereospecific synthesis of specifically deuterated metoprolol enantiomers from chiral starting materials

H. Umesha Shetty, Satya S. Murthy, Wendel L. Nelson

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1989

Language:

english

File:

PDF, 582 KB

english, 1989

9

Synthesis of [2H5]arecoline for use as internal standard in mass spectrometric assay

H. Umesha Shetty, Timothy T. Soncrant, Nigel H. Greig, Stanley I. Rapoport

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1990

Language:

english

File:

PDF, 331 KB

english, 1990

10

Synthesis of deuterium-labeled prochlorperazine

Edward M. Hawes, Trevor S. Gurnsey, H. Umesha Shetty, Kamal K. Midha

Journal:

Journal of Pharmaceutical Sciences

Year:

1983

Language:

english

File:

PDF, 248 KB

english, 1983

11

Synthesis of deuterium-labeled fluphenazine

H. Umesha Shetty, Edward M. Hawes, Kamal K. Midha

Journal:

Journal of Pharmaceutical Sciences

Year:

1984

Language:

english

File:

PDF, 550 KB

english, 1984

12

Attempts to use cyanide ion to trap imine intermediates in the microsomal N-dealkylation of propranolol: Formation of α-aminonitriles as artifacts when using ether for extraction

H. Umesha Shetty, Wendel L. Nelson

Journal:

Journal of Pharmaceutical Sciences

Year:

1985

Language:

english

File:

PDF, 534 KB

english, 1985

13

An automatic reaction control chemical ionization technique in ion trap detector for quantitative plasma profding of arecoline in treated alzheimer patients

H.Umesha Shetty, Eileen M. Daly, Nigel H. Greig, Stanley I. Rapoport, Timothy T. Soncrant

Journal:

Journal of the American Society for Mass Spectrometry

Year:

1991

Language:

english

File:

PDF, 658 KB

english, 1991

14

Identification of Two Molecular Species of Rat Brain Phosphatidylcholine that Rapidly Incorporate and Turn Over Arachidonic Acid In Vivo

H. Umesha Shetty, Quentin R. Smith, Kazushige Washizaki, Stanley I. Rapoport, A. David Purdon

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 886 KB

english, 1996

15

Development of lipophilic anticancer agents for the treatment of brain tumors by the esterification of water-soluble chlorambucil

Shigeru Genka, Joseph Deutsch, Umesha H. Shetty, Paul L. Stahle, Varghese John, Ivan M. Lieberburg, Francis Ali-Osmant, Stanley I. Rapoport, Nigel H. Greig

Journal:

Clinical and Experimental Metastasis

Year:

1993

Language:

english

File:

PDF, 933 KB

english, 1993

16

Brain and plasma pharmacokinetics and anticancer activities of cyclophosphamide and phosphoramide mustard in the rat

Shigeru Genka, Joseph Deutsch, Paul L. Stahle, Umesha H. Shetty, Varghese John, Cynthia Robinson, Stanely I. Rapoport, Nigel H. Greig

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 933 KB

english, 1990

17

Brain uptake and anticancer activities of vincristine and vinblastine are restricted by their low cerebrovascular permeability and binding to plasma constituents in rat

Nigel H. Greig, Timothy T. Soncrant, H. Umesha Shetty, Seiji Momma, Quentin R. Smith, Stanley I. Rapoport

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 668 KB

english, 1990

18

Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I

H. Umesha Shetty, Sami S. Zoghbi, Jeih-San Liow, Masanori Ichise, Jinsoo Hong, John L. Musachio, Christer Halldin, Jurgen Seidel, Robert B. Innis, Victor W. Pike

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2007

Language:

english

File:

PDF, 311 KB

english, 2007

19

Synthesis and initial evaluation of [11C](R)-RWAY in monkey—a new, simply labeled antagonist radioligand for imaging brain 5-HT1Areceptors with PET

Julie A. McCarron, Sami S. Zoghbi, H. Umesha Shetty, Eric S. Vermeulen, Håkan V. Wikström, Masanori Ichise, Fumihiko Yasuno, Christer Halldin, Robert B. Innis, Victor W. Pike

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

2007

Language:

english

File:

PDF, 409 KB

english, 2007

20

Measuring Brain Uptake and Incorporation into Brain Phosphatidylinositol of Plasmamyo-[2H6]Inositol in Unanesthetized Rats: An Approach to Estimate In

Kaizong Ma, Joseph Deutsch, Nelly E. Villacreses, Thad A. Rosenberger, Stanley I. Rapoport, H. Umesha Shetty

Journal:

Neurochemical Research

Year:

2006

Language:

english

File:

PDF, 186 KB

english, 2006

21

Investigation of the Metabolites of (S,S)-[11C]MeNER in Humans, Monkeys and Rats

Magnus Schou, Sami S. Zoghbi, H. Umesha Shetty, Evgeny Shchukin, Jeih-San Liow, Jinsoo Hong, Bengt A. Andrée, Balázs Gulyás, Lars Farde, Robert B. Innis, Victor W. Pike, Christer Halldin

Journal:

Molecular Imaging and Biology

Year:

2009

Language:

english

File:

PDF, 183 KB

english, 2009

22

High-performance liquid chromatographic analysis of chlorambucil tert.-butyl ester and its active metabolites chlorambucil and phenylacetic mustard in plasma and tissue

Nigel H. Greig, Paul L. Stahle, H. Umesha Shetty, Shigeru Genka, Varghese John, Timothy T. Soncrant, Stanley I. Rapoport

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1990

Language:

english

File:

PDF, 537 KB

english, 1990

23

In Vivo Imaging of Fatty Acid Incorporation into Brain to Examine Signal Transduction and Neuroplasticity Involving Phospholipids

STANLEY I. RAPOPORT, DAVID PURDON, H. UMESHA SHETTY, ERIC GRANGE, QUENTIN SMITH, COLLINS JONES, MICHAEL C. J. CHANG

Journal:

Annals of the New York Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.44 MB

english, 1997

24

Selection of downy mildew resistant somaclones, from a susceptible B line of pearl millet

S. Umesha, K.C. Nagarathna, Sudheer A. Shetty, H. Shekar Shetty

Journal:

Plant Cell, Tissue and Organ Culture

Year:

1999

Language:

english

File:

PDF, 36 KB

english, 1999

25

Ts65Dn Mouse, a Down Syndrome Model, Exhibits Elevated myo-Inositol in Selected Brain Regions and Peripheral Tissues

H. Umesha Shetty, Richard J. Siarey, Zygmunt Galdzicki, Jim Stoll, Stanley I. Rapoport

Journal:

Neurochemical Research

Year:

2000

Language:

english

File:

PDF, 47 KB

english, 2000

26

Free radical metabolism of raloxifene in human liver microsomes

Lim, Heng-Keang, Yang, Min, Lam, Wing, Xu, Fran, Chen, Jie, Xu, Yaodong, Shetty, H. Umesha, Yang, Ke, Silva, Jose, Evans, David C.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.33 MB

english, 2012

27

Phospholipid composition and levels are altered in down syndrome brain

Eric J. Murphy, Mark B. Schapiro, Stanley I. Rapoport, H.Umesha Shetty

Journal:

Year:

2000

Language:

english

File:

PDF, 116 KB

english, 2000

28

Chemical and stereochemical aspects of propranolol metabolism. Diastereomeric 1-(1-hydroxy-2-propylamino)-3-(1-naphthoxy)-2-propanols produced by rat liver microsomal .omega.-hydroxylation

Shetty, H. Umesha, Nelson, Wendel L.

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 674 KB

english, 1986

29

Synthesis and Evaluation in Monkey of Two Sensitive 11C-Labeled Aryloxyanilide Ligands for Imaging Brain Peripheral Benzodiazepine Receptors In Vivo

Briard, Emmanuelle, Zoghbi, Sami S., Imaizumi, Masao, Gourley, Jonathan P., Shetty, H. Umesha, Hong, Jinsoo, Cropley, Vanessa, Fujita, Masahiro, Innis, Robert B., Pike, Victor W.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 333 KB

english, 2008

30

Enantioselective and diastereoselective aspects of the oxidative metabolism of metoprolol

Satya S. Murthy, H.Umesha Shetty, Wendel L. Nelson, peter R. Jackson, Martin S. Lennard

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 828 KB

english, 1990

31

Transmission of seed-borne infection of muskmelon by Didymella bryoniae and effect of seed treatments on disease incidence and fruit yield

J. Sudisha, S.R. Niranjana, S. Umesha, H.S. Prakash, H. Shekar Shetty

Journal:

Biological Control

Year:

2006

Language:

english

File:

PDF, 833 KB

english, 2006

32

Effects of ketoconazole on the biodistribution and metabolism of [11C]loperamide and [11C]N-desmethyl-loperamide in wild-type and P-gp knockout mice

Nicholas Seneca, Sami S. Zoghbi, H. Umesha Shetty, Edward Tuan, Pavitra Kannan, Andrew Taku, Robert B. Innis, Victor W. Pike

Journal:

Nuclear Medicine and Biology

Year:

2010

Language:

english

File:

PDF, 521 KB

english, 2010

33

Pharmacokinetics of methyl palmoxirate, an inhibitor of β-oxidation, in rats and humans

Michael C.J. Chang, Catherine Connolly, David Hill, A.David Purdon, Takanori Hayakawa, George Grimes, H.Umesha Shetty

Journal:

Year:

1998

Language:

english

File:

PDF, 437 KB

english, 1998

34

Lytic activity in pearl millet: its role in downy mildew disease resistance

S Umesha, M Shylaja Dharmesh, H Shekar Shetty

Journal:

Year:

2000

Language:

english

File:

PDF, 158 KB

english, 2000

35

Biocontrol of downy mildew disease of pearl millet using Pseudomonas fluorescens

S. Umesha, Shylaja M. Dharmesh, Sudheer A. Shetty, M. Krishnappa, H.Shekar Shetty

Journal:

Crop Protection

Year:

1998

Language:

english

File:

PDF, 665 KB

english, 1998

36

Comparison of human plasma arterial input function for [11C]MePPEP determined with LC-MS/MS and radiometric methods

Victor W. Pike, Sami S. Zoghbi, H. Umesha Shetty, Jussi Hirvonen, Kacey B. Anderson, Kimberly J. Jenko, Cheryl Morse, Robert B. Innis

Journal:

Year:

2010

Language:

english

File:

PDF, 174 KB

english, 2010

37

Plastic fats from sal, mango and palm oil by lipase catalyzed interesterification

Umesha Shankar Shetty, Yella Reddy Sunki Reddy…

Journal:

Journal of Food Science and Technology

Year:

2014

Language:

english

File:

PDF, 376 KB

english, 2014

38

Characterization of fast-decaying PET radiotracers solely through LC-MS/MS of constituent radioactive and carrier isotopologues

H Umesha Shetty, Cheryl L Morse, Yi Zhang, Victor W Pike

Journal:

EJNMMI Research

Year:

2013

Language:

english

File:

PDF, 302 KB

english, 2013

39

Innovation Award 2012

Umesha, Shankar Shetty, Naidu, K. Akhilender

Journal:

Österreichische Wasser- und Abfallwirtschaft

Year:

2013

Language:

german

File:

PDF, 662 KB

german, 2013

40

Antioxidants and antioxidant enzymes status of rats fed on n-3 PUFA rich Garden cress (Lepidium Sativum L) seed oil and its blended oils

Umesha, Shankar Shetty, Naidu, K. Akhilender

Journal:

Journal of Food Science and Technology

Year:

2015

Language:

english

File:

PDF, 299 KB

english, 2015

41

öwav-kalender

Umesha, Shankar Shetty, Naidu, K. Akhilender

Journal:

Österreichische Wasser- und Abfallwirtschaft

Year:

2013

Language:

german

File:

PDF, 606 KB

german, 2013

42

Synthesis and Evaluation of Two 18 F-Labeled 6-Iodo-2-(4‘- N , N -dimethylamino)phenylimidazo[1,2- a ]pyridine Derivatives as Prospective Radioligands for β-Amyloid in Alzheimer's Disease

Cai, Lisheng, Chin, Frederick T., Pike, Victor W., Toyama, Hiroshi, Liow, Jeih-San, Zoghbi, Sami S., Modell, Kendra, Briard, Emmanuelle, Shetty, H. Umesha, Sinclair, Kathryn, Donohue, Sean, Tipre, Dny

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 332 KB

english, 2004

43

Measurement of myo -Inositol Turnover in Phosphatidylinositol: Description of a Model and Mass Spectrometric Method for Cultured Cortical Neurons

Chikhale, Elsbeth G., Balbo, Andrea, Galdzicki, Zygmunt, Rapoport, Stanley I., Shetty, H. Umesha

Journal:

Year:

2001

Language:

english

File:

PDF, 63 KB

english, 2001

44

Single-Step High-Yield Radiosynthesis and Evaluation of a Sensitive 18 F-Labeled Ligand for Imaging Brain Peripheral Benzodiazepine Receptors with PET

Briard, Emmanuelle, Zoghbi, Sami S., Siméon, Fabrice G., Imaizumi, Masao, Gourley, Jonathan P., Shetty, H. Umesha, Lu, Shuiyu, Fujita, Masahiro, Innis, Robert B., Pike, Victor W.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 338 KB

english, 2009

45

Synthesis and Evaluation of N -Methyl and S -Methyl 11 C-Labeled 6-Methylthio-2-(4′- N , N -dimethylamino)phenylimidazo[1,2- a ]pyridines as Radioligands for Imaging β-Amyloid Plaques in Alzheimer’s Disease

Cai, Lisheng, Liow, Jeih-San, Zoghbi, Sami S., Cuevas, Jessica, Baetas, Cesar, Hong, Jinsoo, Shetty, H. Umesha, Seneca, Nicholas M., Brown, Amira K., Gladding, Robert, Temme, Sebastian S., Herman, Mar

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 383 KB

english, 2008

46

Chemical aspects of metoprolol metabolism. Asymmetric synthesis and absolute configuration of the 3-[4-(1-hydroxy-2-methoxyethyl)phenoxy]-1-(isopropylamino)-2-propanols, the diastereomeric benzylic hydroxylation metabolites

Shetty, H. Umesha, Nelson, Wendel L.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 713 KB

english, 1988

47

Transmission of seed-borne infection of chilli by Burkholderia solanacearum and effect of biological seed treatment on disease incidence

Umesha, S., Kavitha, R., Shetty, H. S.

Journal:

Archives of Phytopathology and Plant Protection

Year:

2005

Language:

english

File:

PDF, 299 KB

english, 2005

48

18F-FCWAY, a serotonin 1A receptor radioligand, is a substrate for efflux transport at the human blood-brain barrier

Liow, Jeih-San, Zoghbi, Sami S., Hu, Shuo, Hall, Matthew D., Hines, Christina S., Shetty, H. Umesha, Araneta, Maria D., Page, Emily M., Pike, Victor W., Kreisl, William C., Herscovitch, Peter, Gottesm

Journal:

Year:

2016

Language:

english

File:

PDF, 886 KB

english, 2016

49

Brain accumulation of myo-inositol in the trisomy 16 mouse, an animal model of Down's syndrome

SHETTY, H. Umesha, HOLLOWAY, Harold W., ACEVEDO, Larisa D., GALDZICKI, Zygmunt

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 227 KB

english, 1996

50

Virtual Screening and Biological Evaluation of Piperazine Derivatives as Human Acetylcholinesterase Inhibitors

Varadaraju, Kavitha Raj, Kumar, Jajur Ramanna, Mallesha, Lingappa, Muruli, Archana, Mohana, Kikkeri Narasimha Shetty, Mukunda, Chethan Kumar, Sharanaiah, Umesha

Journal:

International Journal of Alzheimer's Disease

Year:

2013

Language:

english

File:

PDF, 2.29 MB

english, 2013